中文版
Signaling Pathways
BIX-01294
Catalog No. :
CL2754
Product Name :
BIX-01294
CAS No. :
935693-62-2
Synonyms :
Chemical Name :
Molecular Formula :
C28H38N6O2
Molecular Weight :
490.64
Molecular Structure :
Appearance :
White to off-white powder
Specification :
98+%
Application :
Registration :
Storage Condition :

BIX-01294 is a reversible and highly selective G9a and GLP Histone Methyltransferase inhibitor, with IC50s of of 1.7 μM and 0.9 μM, respectively. BIX-01294 inhibits G9a/GLP by competing for binding with the amino acids N-terminal of the substrate lysine residue. BIX-01294, a (1H-1,4-diazepin-1-yl)-quinazolin-4-yl amine derivative, induces necroptosis and autophagy. BIX-01294 has antitumor activity in recurrent tumor cells。

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->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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