Catalog No. :	CL1001
Product Name :	Brefeldin A
CAS No. :	20350-15-6
Synonyms :	BFA
Chemical Name :	(1S,2E,7S,10E,12R,13R,15S)-12,15-Dihydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one
Molecular Formula :	C16H24O4
Molecular Weight :	280.36
Molecular Structure :
Appearance :	Off-white powder
Specification :	98+%
Application :	Autophagy | CRISPR/Cas9 | Mitophagy | HSV | Antibiotic | Bacterial
Registration :
Storage Condition :	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR.

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