中文版
Signaling Pathways
Erastin
Catalog No. :
CL2661
Product Name :
Erastin
CAS No. :
571203-78-6
Synonyms :
Chemical Name :
Molecular Formula :
C30H31ClN4O4
Molecular Weight :
547.04
Molecular Structure :
Appearance :
White to off-white powder
Specification :
98+%
Application :
Registration :
Storage Condition :

Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity

Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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