Catalog No. :	CL1006
Product Name :	Laduviglusib
CAS No. :	252917-06-9
Synonyms :	CHIR-99021 (CT99021)
Chemical Name :
Molecular Formula :	C22H18Cl2N8
Molecular Weight :	465.34
Molecular Structure :
Appearance :	Off-white to light brown powder
Specification :	99+%
Application :
Registration :
Storage Condition :

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.

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