中文版
Signaling Pathways
LY2109761
Catalog No. :
CL1900
Product Name :
LY2109761
CAS No. :
700874-71-1
Synonyms :
Chemical Name :
Molecular Formula :
C26H27N5O2
Molecular Weight :
441.52
Molecular Structure :
Appearance :
White to yellow powder
Specification :
98+%
Application :
Registration :
Storage Condition :

LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM in a cell-free assay, respectively; shown to negatively affect the phosphorylation of Smad2. LY2109761 blocks autophagy and induces apoptosis.

Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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