Catalog No. :	CL2563
Product Name :	Capecitabine
CAS No. :	154361-50-9
Synonyms :	Capecitabine
Chemical Name :	pentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate
Molecular Formula :	C15H22FN3O6
Molecular Weight :	359.35
Molecular Structure :
Appearance :	White to off-white solid
Specification :	99+%
Application :	Anti-cancer | DNA/RNA Synthesis inhibitor | Apoptosis related activator
Registration :
Storage Condition :	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.

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