Catalog No. :
|
CL1798 |
Product Name :
|
N-Acetyl-Calicheamicin |
CAS No. :
|
108212-76-6 |
Synonyms :
|
N-Acetyl-Calicheamicin γ | N-Acetyl-γ-calicheamicin |
Chemical Name :
|
S-((2R,3S,4S,6S)-6-((((2R,3S,4S,5R,6R)-5-(((2S,4S,5S)-5-(N-ethylacetamido)-4-methoxytetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-6-(((2S,5Z,9R,13Z)-9-hydroxy-12-((methoxycarbonyl)amino)-13-(2-(methyltrisulfanyl)ethylidene)-11-oxobicyclo[7.3.1]trideca-1(12),5-dien-3,7-diyn-2-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl)amino)oxy)-4-hydroxy-2-methyltetrahydro-2H-pyran-3-yl) 4-(((2S,3R,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3-iodo-5,6-dimethoxy-2-methylbenzothioate |
Molecular Formula :
|
C57H76IN3O22S4 |
Molecular Weight :
|
1410.39 |
Molecular Structure :
|
|
Appearance :
|
White to off-white powder |
Specification :
|
98+% |
Application :
|
Cancer Targeted Therapy |
Registration :
|
|
Storage Condition :
|
4°C, sealed storage, away from moisture |
N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ), an enediyne anti-tumor antibiotic, is an ADC cytotoxin. N-Acetyl-Calicheamicin can induce DNA damage, and can be used in the synthesis of ADC.
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