Catalog No. :	CL1950
Product Name :	坦螺旋霉素
CAS No. :	75747-14-7
Synonyms :	Tanespimycin (17-AAG); CP127374; NSC-330507; KOS 953​
Chemical Name :	17-Demethoxy-17-(2-propenylamino)geldanamycin;17-(Allylamino)-17-demethoxygeldanamycin
Molecular Formula :	C31H43N3O8
Molecular Weight :	585.69
Molecular Structure :
Appearance :	Purple to purplish red solid
Specification :	98+%
Application :
Registration :
Storage Condition :	4°C, protect from light

Tanespimycin (17-AAG, CP127374, NSC-330507, KOS 953) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Tanespimycin (17-AAG) induces apoptosis, necrosis, autophagy and mitophagy. Phase 3.

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