Catalog No. :
|
HL1009 |
Product Name :
|
Cyclopamine (11-deoxojervine) |
CAS No. :
|
4449-51-8 |
Synonyms :
|
11-Deoxojervine |
Chemical Name :
|
(2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3',6',10,11b-tetramethyl-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol |
Molecular Formula :
|
C27H41NO2 |
Molecular Weight :
|
411.62 |
Molecular Structure :
|
|
Appearance :
|
White to off-white powder |
Specification :
|
98+% |
Application :
|
Hedgehog/Smoothened antagonist |
Registration :
|
|
Storage Condition :
|
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids.
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