中文版
Natural Bulk Compounds
Cyclopamine (11-deoxojervine)
Catalog No. :
HL1009
Product Name :
Cyclopamine (11-deoxojervine)
CAS No. :
4449-51-8
Synonyms :
11-Deoxojervine
Chemical Name :
(2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3',6',10,11b-tetramethyl-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol
Molecular Formula :
C27H41NO2
Molecular Weight :
411.62
Molecular Structure :
Appearance :
White to off-white powder
Specification :
98+%
Application :
Hedgehog/Smoothened antagonist
Registration :
Storage Condition :
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Cyclopamine (11-Deoxojervine), a Smoothened (Smo) antagonist (IC50: 46 nM in TM3Hh12 cells), belongs to the group of steroidal jerveratrum alkaloids. 

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