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Signaling Pathways
Nintedanib (BIBF 1120)
Catalog No. :
CL1034
Product Name :
Nintedanib (BIBF 1120)
CAS No. :
656247-17-5
Synonyms :
BIBF 1120
Chemical Name :
(Z)-methyl 3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
Molecular Formula :
C31H33N5O4
Molecular Weight :
539.6248
Molecular Structure :
Appearance :
Yellow crystalline powder
Specification :
98+%
Application :
VEGFR inhibitor | FGFR inhibitor| PDGFR inhibitor | Src inhibitor
Registration :
Storage Condition :
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.

Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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