Catalog No. :
|
CL1123 |
Product Name :
|
Lurbinectedin |
CAS No. :
|
497871-47-3 |
Synonyms :
|
PM01183 |
Chemical Name :
|
(1'R,6R,6aR,7R,13S,14S,16R)-5-(Acetyloxy)-2',3',4',6,6a,7,9'-decahydro-8,14-dihydroxy-6',9-dimethoxy-4,10,23-trimethyl-spiro(6,16-(epithiopropaneoxymethano)-7.13-imino-12H-1,3-dioxolo[7,8]soquino[3,2-b][3]benzazocine-20,1'-[1H]pyrido[3,4-b]indol]-19-one |
Molecular Formula :
|
C41H44N4O10S
|
Molecular Weight :
|
784.87 |
Molecular Structure :
|
|
Appearance :
|
White to light yellow powder |
Specification :
|
98+% |
Application :
|
DNA/RNA Synthesis modulator |
Registration :
|
|
Storage Condition :
|
Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively.
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