Catalog No. :	CL1457
Product Name :	Alectinib
CAS No. :	1256580-46-7
Synonyms :	CH5424802; RO5424802; RG7853
Chemical Name :	9-ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
Molecular Formula :	C30H34N4O2
Molecular Weight :	482.62
Molecular Structure :
Appearance :	White to off-white powder
Specification :	98+%
Application :	ALK inhibitor
Registration :
Storage Condition :	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Alectinib (CH5424802) is a potent, selective, and orally available ALK inhibitor with an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner), and also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration

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