Catalog No. :	CL2373
Product Name :	Midostaurin
CAS No. :	120685-11-2
Synonyms :	PKC412 | CGP 41231 | CGP 41251| CAS 120685-11-2 |PKC
Chemical Name :	N-((5R,7R,8R,9S)-8-methoxy-9-methyl-16-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide
Molecular Formula :	C35H30N4O4
Molecular Weight :	570.64
Molecular Structure :
Appearance :	White to yellow powder
Specification :	98+%
Application :	Anticancer Research
Registration :
Storage Condition :	-20°C, sealed storage, away from moisture

PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor. Midostaurin inhibits protein kinase C alpha (PKCalpha), vascular endothelial growth factor receptor 2 (VEGFR2), c-kit, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinase 3 (FLT3) tyrosine kinases, which may result in disruption of the cell cycle, inhibition of proliferation, apoptosis, and inhibition of angiogenesis in susceptible tumors.

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