中文版
Natural Bulk Compounds
Hyperforin
Catalog No. :
HL1002
Product Name :
Hyperforin
CAS No. :
11079-53-1
Synonyms :
Chemical Name :
(1R,5S,6R,7S)-4-hydroxy-5-isobutyryl-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)bicyclo[3.3.1]non-3-ene-2,9-dione
Molecular Formula :
C35H52O4
Molecular Weight :
536.785
Molecular Structure :
Appearance :
Light yellow to light yellow waxy solid
Specification :
85+%
Application :
Calcium Channel | TRP Channel
Registration :
Storage Condition :
Fill with nitrogen or dissolve in polar solvents and store in a low temperature environment below -30 ℃ away from light.

Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model. 

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