Catalog No. :	CL1372
Product Name :	Trabectedin
CAS No. :	114899-77-3
Synonyms :	Ecteinascidin 743 | ET-743
Chemical Name :	Ecteinascidin 743
Molecular Formula :	C39H43N3O11S
Molecular Weight :	761.84
Molecular Structure :
Appearance :	White to light yellow powder
Specification :	98+%
Application :	Antitumor activity
Registration :
Storage Condition :	-20°C, protect from light, stored under nitrogen

Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has the potential for soft tissue sarcoma and ovarian cancer research.

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