Catalog No. :	CL2725A
Product Name :	Exatecan Mesylate
CAS No. :	169869-90-3
Synonyms :	DX8951f
Chemical Name :
Molecular Formula :	C25H26FN3O7S
Molecular Weight :	531.55
Molecular Structure :
Appearance :	Light yellow to green yellow solid
Specification :	99+%
Application :
Registration :
Storage Condition :

 Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues

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