中文版
Signaling Pathways
Fludarabine
Catalog No. :
CL3046
Product Name :
Fludarabine
CAS No. :
21679-14-1
Synonyms :
Fara A | Fludarabinum | Fludarabine | F-ara-A | NSC 118218 Base
Chemical Name :
(2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
Molecular Formula :
C10H12FN5O4
Molecular Weight :
285.23
Molecular Structure :
Appearance :
White to yellow powder
Specification :
98+%
Application :
Antineoplastic Agents
Registration :
Storage Condition :
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes.


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