Catalog No. :	CL2201
Product Name :	Pomalidomide
CAS No. :	19171-19-8
Synonyms :	| CC-4047 | 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide; 4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
Chemical Name :	4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Molecular Formula :	C13H11N3O4
Molecular Weight :	273.24
Molecular Structure :
Appearance :	Yellow powder
Specification :	98+%
Application :	Anti-tumor research | Ligands for E3 Ligase | Molecular Glues | Apoptosis
Registration :
Storage Condition :	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in PBMCs. Pomalidomide can be utilized in PROTAC as a ligand for targeting E3 ligase and inhibiting the E3 ligase protein cereblon (CRBN). Pomalidomide promotes apoptosis and cell cycle arrest.

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