中文版
Signaling Pathways
Resmetirom
Catalog No. :
CL3038
Product Name :
Resmetirom
CAS No. :
920509-32-6
Synonyms :
MGL-3196 | VIA-3196
Chemical Name :
2-(3,5-dichloro-4-((5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile
Molecular Formula :
C17H12Cl2N6O4
Molecular Weight :
435.22
Molecular Structure :
Appearance :
White to yellow powder
Specification :
98+%
Application :
Thyroid Hormone Receptor
Registration :
Storage Condition :
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Resmetirom (MGL-3196, VIA-3196) is a liver-directed, orally active, selective thyroid hormone receptor β(THR-β) agonist with an EC50 of 0.21 μM,shows 28-fold selective for THR-β over THR-α in a functional assay.

Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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