Catalog No. :
|
CL1022 |
Product Name :
|
Cabazitaxel |
CAS No. :
|
183133-96-2 |
Synonyms :
|
XRP6258 | RPR-116258A | TXD 258 | Taxoid XRP6258 |
Chemical Name :
|
(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate. |
Molecular Formula :
|
C45H57NO14 |
Molecular Weight :
|
835.93 |
Molecular Structure :
|
|
Appearance :
|
White or off-white solid |
Specification :
|
98+% |
Application :
|
Microtubule Associated inhibitor | Autophagy activator |
Registration :
|
|
Storage Condition :
|
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Cabazitaxel is a semi-synthetic derivative of a natural taxoid that kills cancer cells by inhibiting cell division and growth. Cabazitaxel exerts its effects by inhibiting microtubule growth and assembly, processes that are essential for cells to divide. Cabazitaxel induces autophagy via the PI3K/Akt/mTOR pathway.
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