Catalog No. :
|
CL2416 |
Product Name :
|
Epothilone B (Patupilone) |
CAS No. :
|
152044-54-7 |
Synonyms :
|
(-)-Epothilone B| EPO 906| EPO 906A | Patupilone |
Chemical Name :
|
(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione |
Molecular Formula :
|
C27H41NO6S |
Molecular Weight :
|
507.68 |
Molecular Structure :
|
|
Appearance :
|
White to off-white powder |
Specification :
|
98+% |
Application :
|
Antineoplastic Agent |
Registration :
|
|
Storage Condition :
|
Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Epothilone B is a microtubule stabilizer with a Ki of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation.
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->>Products covered by valid patents are not offered or supplied for commercial use.
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->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.