Catalog No. :	CL2962
Product Name :	Deucravacitinib
CAS No. :	1609392-27-9
Synonyms :	BMS-986165
Chemical Name :	6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide
Molecular Formula :	C20H19D3N8O3
Molecular Weight :	425.46
Molecular Structure :
Appearance :	Off-white to light yellow powder
Specification :	99+%
Application :	JAK inhibitor | IFN inhibitor | Interleukins inhibitor
Registration :
Storage Condition :	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain.

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