中文版
Immunosuppressants
Obeticholic Acid
Catalog No. :
CL1437
Product Name :
Obeticholic Acid
CAS No. :
459789-99-2
Synonyms :
INT-747 | 6-ECDCA | 6-Ethylchenodeoxycholic acid
Chemical Name :
(4R)-4-[(3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Molecular Formula :
C26H44O4
Molecular Weight :
420.63
Molecular Structure :
Appearance :
White to off-white powder
Specification :
98+%
Application :
FXR agonist | Autophagy inhibitor
Registration :
Storage Condition :
Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Obeticholic Acid (INT747; 6-ECDCA) is a novel derivative of cholic acid which acts as a potent and selective FXR agonist displaying anticholeretic activity in an in vivo rat model of cholestasis. It inhibits vascular smooth muscle cell inflammation and migration as well as promotes adipocyte differentiation and regulates adipose cell function in vivo.

Statement:
->>Products covered by valid patents are not offered or supplied for commercial use.
->>Products currently covered by valid US Patents are offered for laboratory R&D use in accordance with 35 USC 271(e)+A13(1).
->>Any patent infringement and resulting liability is solely at buyer's risk.
->>Our products are only raw materials for drugs or industry, can't be used for human or animals directly.

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